What is Retinochoroiditis?
When the retina gets inflamed and extends to the choroid it is known as retinochoroiditis. As a result of the inflammation, the choroid contains sensory retina which becomes opaque and edematous. In a later stage, the inflamed cells burst through the sensory retina and populate the vitreous body.
A person suffering from toxoplasma retinochoroiditis experiences blurred vision. The eye becomes red as the cells burst through the sensory retina.
Below are a few possible causes of toxoplasma retinochoroiditis and there can also be other causes so consult your doctor:-
- HIV infection
- Poor immunity
- Immunocompromised patients
- Low CD4+ cell count
Below are a few possible treatments for toxoplasma retinochoroiditis:-
- Foline Acid - In transformylation reactions, the folic acid acts like a formyl group carrier which contains calcium salt and leucovorin calcium. This has therapeutic use. It is metabolically active as it contains I-leucovorin which is also known as levoleucovorin. It therefore doesn’t require bioactivation, an enzyme contained in the folic acid. This agent enhances the effect of fluoropyrimidines making it stable, thus attaching to the enzyme thymidylate synthase.
- Pyrimethamine - This is one of the folic acid antagonists which is used to treat retinochoroiditis and is also used as antimalarial.
- Clindamycin - Clindamycin is from the bacterial ribosome, thus it disrupts the bacterial protein sunthesis.
- Sulfadiazine - This is a drug which is used in treating pneumonia and meningitis as well as other infections. Sulfadiazine, a short acting bacteriostatic inhibits bacterial folic sunthesis by fighting with para amino benzoic acid. It is combined with pyrimethamine to treat toxoplasma retinochoroiditis.
- Trimethoprim - This is an antibacterial which is combined with sulfonamide to treat infections like urinary tract infection. It is also used to treat toxoplasma retinochoroiditis along with other combinations.
- Cotrimoxzole- It’s a combination of two antibacterial agents- sulfamethoxazole and trimethoprim.
- Sulfamethoxazole - This is also an antibacterial agent which is combined with folic acid synthesis. It has less development to resistance.
- Cryotherapy - It combines general and local use of cold to treat the disease.
- Retinal Laser Photocoagulation - It is the use of laser light around the tear in the retina which develops the scar tissue and attaches the retina to the eye wall.
- Vitrectomy - It is removing the gel-like substance from the inner surface of the eye to control the bleeding of vitreous cavity or to detach the retina. A gel-like substance is injected to bring the retina in place against the wall of the eye.