Eye Deceases

(H49.3-4) Ophthalmoparesis

What is Ophthalmoparesis

The muscles that are responsible for the movement of one or both the eyes get paralyzed, it is known as ophthalmoparesis. Ophthalmoparesis is also known as mitochondrial encephalomyelopathy with ophthalmoplegia or progressive external ophthalmoplegia.

ICD-10 H49.3-H49.4
ICD-9 367.52, 376.22, 378.55, 378.56, 378.72, 378.86, 378.9
DiseasesDB 9240
MeSH D009886

This problem is related to the neurologic system and often known as “ophthalmoplegia plus”.  This disorder often affects both the eyes and leads to paralysis of both eyes.  

Causes of Ophthalmoparesis

There are a few causes related to ophthalmoparesis which are given below:-

When the muscles degenerate or there is muscle biopsy, it causes ophthalmoplegia. In this a tiny piece of muscle is removed and examined under the microscope which appears to look like ragged red fibers to check its characteristic.

On the other hand, people also suffer from progressive external ophthalmoplegia which is related to neurologic syndromes.

Vitamin B12 Deficiency - Vitamin B12 is very important for good health and it is most likely to be the cause of ophthalmoparesis. A deficiency of vitamin B12 can result in anemia which is also known as pernicious anemia. A deficiency of vitamin B12 happens when the body is unable to absorb vitamin B12 or there is a lack of vitamin B12 in the diet. Vitamin B12 is important for the production of red blood cells in the body.

Aarskog Syndrome - This is a genetic condition which is rare and is characterized by hand, facial, genital and growth abnormalities.  This syndrome is connected to ophthalmoparesis in an indirect way and starts affecting gradually.

Symptoms of Ophthalmoparesis

The first symptom of ophthalmoparesis is seen before 15 years. Mostly external ophthalmoplegia syndrome is known to be controlled by DNA in mitochondia. Mostly inherited diseases are transferred by DNA in the cell nucleus. It is usually transferred from the mother to the fetus. Even till today, it is still unknown as to why a few forms of neuogenic are myopathic.

Other symptoms of ophthalmoplegia are- thyroid disease, progressive supranuclear palsy, brainstem tumors, diabetes mellitus, migraine, pituitary stroke and basilar artery stroke.

Ophthalmoparesis Treatment

Unfortunately, there is no cure for ophthalmoparesis. Experts believe that vitamin E therapy is used to cure Kearns-Sayre syndrome. Even, the use of coenzyme Q which is a natural substance almost like vitamin K is used to treat a few forms of ophthalmoparesis but it depends on the difference it shows.

A surgery can be performed to lift drooping eyelids or the patient can also use a patch to avoid double vision. Ophthalmoparesis is a kind of disease which has no prevention; therefore it may suddenly occur to anyone.