Leber’s hereditary optic neuropathy is a condition that causes loss of the central vision and it is a rare condition. It mostly affects men especially in late twenties or early thirties. The symptoms of Leber’s hereditary optic neuropathy can occur at any age to either women or men.
Leber’s hereditary optic neuropathy usually affects first one eye; therefore the central vision is lost in a couple of weeks. After a week or two later, the second eye also gets affected. When a person loses his eye sight, it is known as the ‘acute’ period. After a couple of weeks, the damage of the eyesight reaches its peak and stops getting worse.
In LHON, it can affect anyone suddenly or gradually over a couple of years. LHON is connected to many genes, all in the DNA zone known as mitochondria. The particular genes change links to LHON which reduce the energy level to the cells of the retina and the optic nerve. These cells constantly need energy and therefore if they do not get, they may get damaged and die. When the retina and the optic nerve get damaged, it causes symptoms of LHON.
LHON is known to be a very rare genetic condition which is passed from the family. It affects 1 in 30,000 to 50,000 people. Though LHON is a genetic condition, not every family member may lose their eyesight and it cannot be told who can get its symptoms.
LHON is inherited through a gene which is passed from the egg cell through the mother. The below causes can be similar or related with LHON
A very obvious symptom is a loss of central vision.
Unfortunately, there is no treatment for Leber’s hereditary optic neuropathy. Glaucoma is one of the forms of LHON that have been studied in a broad manner. Many neuroprotective agents who have been used to investigate other diseases may help in LHON therapy.