CLA is known for its body weight management properties. It includes reducing body fat and also increasing lean muscle mass. Studies have been conducted on mice and rats. Studies have shown the progress of problems like tumours in mammary, skin and colon tissues. Studies have also found that it may have anti-cancer properties. Mainly the target effect of the Conjugated Linoleic Acid is on the belly firmness.
This acid is mainly used for weight management. Different studies conducted on dose and duration of the Conjugated Linoleic Acid has yielded different results. Results have shown reduction in total body fat and increase in lean body mass.
Some researchers have also found no positive results because of many reasons like duration of the research, dose of the medicine and the instrument used to check the change may also not be sensitive to check slight changes.
Dose of Conjugated Linoleic Acid used in clinical trials ranged from 3 to about 6.8 g daily of a ratio of 50:50 or may be at least equal amounts of cis-9, trans-11 and trans-10, cis-12 isomers. The typical dosage of Conjugated Linoleic Acid supplement is 1-2 g daily, though daily dosage which has been used is 6-7g daily. Previously trials have found that dosage of 3.4g of a CLA isomer mixture is helpful in improving the body composition, if a person takes a higher dose side effects would be disastrous.
Adverse effects or side effects of CLA are gastrointestinal, it may also include nausea, dyspepsia, diarrhoea and loose motions. Patients who are diabetic or have cardiovascular problem should avoid CLA usage. People who are plan to start a weight loss programme by using Conjugated Linoleic Acid should first consult the doctor.