Vitiligo is a disease that causes depigmentation of the skin. Due to the melanocytes the cells may cause skin pigmentation, or even die. The cause of vitiligo is unidentified, but research suggests that it may cause due to autoimmune, genetic, oxidative stress, neural, or viral causes. It occurrence to person less than one percent but most common from is non-segmental vitiligo, it appear in symmetric patches, large areas of the body

Signs and Symptoms

The most common symptom of this disease is disorders affect the color of your skin. At initial stage patches are small but often they will be enlarging and at same time change their shape. Due to skin lesions, area affect such as face, hands and wrists. Most common occurrence of loss of pigment around body orifices, such as

  • Skin
  • Hair (scalp, eyebrow, eyelash, beard)
  • Inside the mouth
  • Genitals

Other less common signs may include:

  • Premature whitening or graying of the hair.
  • Loss of color in the tissues (mucous membranes).
  • Loss of or change in color in retina.


Non-segmental vitiligo is usually some shape of regularity in the location of the patches in the skin. The patches also come into view by time on over large portions or some particular areas of the body. In this condition little pigmented skin remains is mention to as vitiligo universalis and may occur at any age.

Classes of non-segmental vitiligo include:

  • Generalized Vitiligo:
  • Universal Vitiligo
  • Focal Vitiligo
  • Acrofacial Vitiligo
  • Mucosal Vitiligo

Differential Diagnosis

Conditions with similar symptoms include:

  • Pityriasis alba
  • Tuberculoid leprosy
  • Postinflammatory hypopigmentation
  • Tinea versicolor
  • Albinism
  • piebaldism
  • idiopathic guttate hypomelanosis
  • progressive macular hypomelanosis
  • Primary adrenal insufficiency


There are a various treatments for vitiligo but most effective treatment is steroids and ultraviolet light in combination with creams. Higher risk due to the vitiligo is skin cancer; the NHS suggests that the primary ineffective treatment is phototherapy and such as

  • Immune mediators
  • Skin camouflage
  • De-pigmenting
  • Transplanting melanocytes

Medical Therapies

  • Topical steroid therapy
  • Psoralen photochemotherapy.
  • Topical psoralen photochemotherapy.
  • Oral psoralen photochemotherapy.
  • Depigmentation

Surgical Therapies

  • Autologous skin grafts
  • Skin grafts using blisters.
  • Micropigmentation
  • Autologous melanocyte transplants

Additional Therapies

  • Sunscreens
  • Cosmetics
  • Counseling and support groups.